Herpes and vaginal delivery and prolonged presence in serum and cerebrospinal fluid. The lowest Herpes and vaginal delivery of neonatal transmission occurs in the setting where the mother has an active infection that was acquired before pregnancy or at stages of gestation before the onset of labour. What appears to be a new infection is occasionally an old one that is causing symptoms for the first time. Neonatal herpes disease following maternal antenatal antiviral suppressive therapy: Ask that a vacuum or forceps not be used during delivery unless medically necessary. Use condoms from start to finish every time you have sexual contact, even if you have no herpes symptoms.